A few years ago I moved to a new city without knowing anyone and worked for a company remotely from a home office. Other than my therapist and saying "hi" to the person at the desk of the yoga studio I went to, I pretty much didn't interact with another human in person for a number of months. In a way, it prepared me for the mass self isolation the world is currently experiencing.
So for everyone who is self-isolating and working from home, here are some things that I learned from that time to help keep some sanity (and keep track of what day and year it is):
Keep doing as much of your regular morning routine as possible. Wake up at the same time, change out of your pyjamas, go for a run or create a home workout, and use your commute time to do some extra housework or check in on a friend.
Designate one part of your home for workspace and only use it for work. Whether you have a home office, or use a certain chair or part of your dining table, making a physical separation between work and home.
Take your regular lunch break and eat it somewhere besides where you are working. If you normally work through lunch, this is a great time to start that practice. I don't care if you have to set a timer on your phone or cook your meal on the spot instead of pre-making it, take a break.
If you need to talk to colleague about something, try video calling them instead of talking on the phone. Seeing someone's face adds more to your conversation and makes it somewhat more personal. This can also apply to talking to your friends and family.
Don't do household chores during the day. As simple as it would be to do something like switching a load of laundry, remember that you are at work and not home.
End your work day at your regular time and do something to take your mind off of work. I used to finish work at 5:00 and go to a 5:30 yoga class to make sure my computer closed and I got out of my work head. While self-isolating you can arrange to hang out with a neighbour across your driveways or make plans to FaceTime a friend.
Try to talk to someone everyday, whether it's through messaging or video/voice calling (and that someone should be an actual human and not you cat). Physical isolation doesn't have to mean mental isolation.
Hopefully these tips can help you, or give you an idea for something that can work in your life. Stay well out there, and may the odds be ever in your favour.